The scanning
model and the Kozak consensus sequence and how it influences initiation of
translation in eukaryotes
Ribosomes enter
at the 5’end of the mRNA and scan down the RNA to look for the first AUG codon
that is in “good context.” The nucleotides that influence initiation are A/G at
-3 and G at +4.
Diagram the
features of a sequence that facilitates ribosomal frame-shifting in Eukaryotes (only)
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